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Next steps: FDA decision (REDEFINE-1 & 2) expected late 2026 REDEFINE-11 (2.4/2.4 mg) readout in H1 2027 Higher-dose Phase 3 initiation planned H2 2026 Why It Matters: The obesity market is now a high-efficacy battleground, with GLP-1 and dual incretin therapies redefining standards of care
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Combination Therapies There is growing interest in therapies that combine multiple mechanisms of action - such as SGLT-2 inhibitors with DPP-4 inhibitors, GLP-1 receptor agonists with SGLT-2 inhibitors, and more complex combinations
A cDNA that suppresses MPP+ toxicity encodes a vesicular amine transporter
