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2022;45.:S144-s74

DAlessio, Tirzepatide, a dual GIP/GLP-1 receptor co-agonist for the treatment of type 2 diabetes with unmatched effectiveness regrading glycaemic control and body weight reduction

[DOI] [PubMed] [Google Scholar] 72.Schafer R., Schatz H

In the SURMOUNT 1 trial, tirzepatide at doses of 5 mg, 10 mg and 15 mg were evaluated against placebo, with pooled tirzepatide groups resulting in significant decreases in total cholesterol, LDL-C, VLDL-C, FFA, and triglycerides and an increase in HDL-C at week 72 of follow-up [35]

GIP also plays important roles in fat metabolism

[DOI] [PMC free article] [PubMed] [Google Scholar] 21.Yip RG-C, Boylan MO, Kieffer TJ, et al