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Rapid weight loss with GLP1 receptor agonists can come at the cost of skeletal muscle, potentially undermining metabolic and functional outcomes

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Exposures Two cohorts were assembled, with the first composed of patients who started and continued on GLP-1 receptor agonists or DPP-4 inhibitors between 1 January 2007 and 31 December 2020 and the second composed of patients who started and continued on GLP-1 receptor agonists or SGLT-2 inhibitors between 1 January 1 2013 and 31 December 2020

Depression concerns among semaglutide users have sparked important clinical conversations

A retrospective analysis of more than 110,000 women between the ages of 45 and 80 found that those who take GLP-1 medications are about 30% less likely to develop breast cancer than those who do not take GLP-1 medications.

A sizable proportion of patients (23.0 to 62.4%) reached an HbA1c of 1.0 vs