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1 Introduction Rhabdomyolysis is characterized by the breakdown of skeletal muscle fibers, resulting in the release of intracellular contents such as myoglobin and creatine kinase (CK) into the bloodstream ( 2 Case presentation A 66-year-old woman presented to the emergency department with profound weakness, nausea, and repeated vomiting, 1 day after receiving her first subcutaneous dose of tirzepatide (Mounjaro) at a supratherapeutic dose of 15 mg (recommended starting dose: 2.5 mg)

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