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This N-terminal insertion drives conformational changes in the TMD, including the outward movement of transmembrane helix 6 (TM6) and reorganization of TM5 and TM7, that create a binding surface for heterotrimeric G proteins on the intracellular face of the receptor

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By application, the obesity and weight management segment is anticipated to witness fastest growth over the forecast period By end use, the hospitals segment dominated the market with the largest share in 2025