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Description
These data suggest that activation of the HPA axis antagonizes the satiation effect of GLP-1R agonism [819]

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Effects of Glucagon-Like Peptide 1 on Counterregulatory Hormone Responses, Cognitive Functions, and Insulin Secretion during Hyperinsulinemic, Stepped Hypoglycemic Clamp Experiments in Healthy Volunteers

In cellular assays, exendin-4 exhibits similar potency as human GLP-1 in binding to and activating GLP-1R (86)
