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The orexigenic action of ghrelin is mediated through direct stimulation of the orexigenic AgRP/NPY neurons and concomitant inhibition of the anorectic POMC/CART neurons in the ARC (143, 144)
lipoproteins and endotoxins) has been confirmed using HEK-Blue TLR2 and HEKBlue TLR4 cells
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Annu Rev Biochem1998;67:821-55
