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Endocrine (2020) 68(3):51825
Development of unimolecular agents targeting both GIPR and GLP-1R The anti-obesity effects of GIPR antagonism antibody, both alone and in combination with GLP-1RAs, have been demonstrated in preclinical models of mice and monkeys (68, 73)
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First degree relatives of individuals with NASH cirrhosis are also recommended to be screened for advanced fibrosis
