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Meta-analysis of 35 clinical trials demonstrated a modest reduction in LDL cholesterol, total cholesterol, and triglycerides in patients treated with GLP-1 RAs compared to controls (58)

Chin J Liver Dis 2021;13:46-53

Reflecting this difficulty Novartis and Probiodrug had to abandon some of their early drug candidates because they proved unsafe and too toxic (Cordes)

LSU Boyd Professor Dr

This framework explains why some patients see dramatic improvements while others see modest changes

It is currently recommended that all patients with diabetes be screened for advanced fibrosis every 1-2 years
