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This doesnt cause pain because there arent any nerves at the base of the hemorrhoid

This concentration is rarely used for long-term therapy because the high doses required at maintenance would exceed standard syringe capacities, but it has niche applications for people who need extremely precise measurements at low doses or who are splitting vials into multiple smaller doses for cost savings

Thus, we limited the doses of Ex-4 used in these experiments to 20 nmol/kg/day

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