stopped tirzepatide NEW: Stopping (Mounjaro) leads patients to gain back the majority of lost weight. - Patients on tirzepatide lost 21% of their body weight in 36 months When to Stop Tirzepatide: Discontinuation

Side effects like nausea, vomiting, and dehydration are dose-dependent and occur more frequently at higher GLP-1 receptor agonist exposures

This further supports the theory that the central and peripheral GLP-1 systems are not only anatomically but also functionally distinct

GLP-1 receptor agonists are associated with lower dementia rates and improved cognitive outcomes in clinical studies, independent of metabolic improvements (37,43)

When the goal of skin tightening is aligned with wellness goals, like staying in shape and reducing stress, patients are more likely to enjoy the journey

The reasoning: when the tablet dissolves on the tongue, some absorption happens through the oral mucosa (buccal absorption)

APPENDIX 1: TABULATED DATA 22