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Second, chronic inflammation is increasingly recognized as a contributor to depression

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Nutrients 15 , 4601 (2023)

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doi: 10.1016/j.jacc.2023.09.811

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The diminished GLP-1 binding of the GLP-1R R380 ECL3 D mutant was partially restored by Asp 15 Glu substitution and almost fully restored by the Asp 15 Lys and inverted Asp 15 Arg substitutions of GLP-1

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