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Louis Aronne, director of the Comprehensive Weight Control Center at Weill Cornell Medicine and NewYork-Presbyterian, previously told TODAY.com

Check with your doctor: sometimes fatigue signals a deeper issue, like vitamin deficiency or medication adjustments needed

Many GLP-1 users report reduced appetite, smaller meals, and digestive changes

Semaglutide primarily targets the mechanisms involved in glucose regulation, primarily affecting insulin and related hormones

Considerations for GLP-1 Therapy Before starting GLP-1 Injections , patients should: Consult a Healthcare Provider: Discuss your medical history and goals to determine suitability

Tips for Managing Your Medication on Longer Journeys Plan your dosing schedule with your prescriber, pack at least one week's extra supply, stay well hydrated to reduce gastrointestinal side effects, and inform your travel insurer you are carrying a prescription injectable