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An analysis of insurance claims for GLP-1 weight-loss therapy (in patients without diabetes) found only 29% were still on the medication at 1 year, and a mere 15% at 2 years (source)

Evidence that intestinal glucagonlike peptide-1 plays a physiological role in satiety

Avoid areas with scars, bruises, or skin abnormalities

Common gastrointestinal adverse effects associated with semaglutide include: Nausea (reported in up to 44% of patients on Wegovy, 20% on Ozempic, and 15% on Rybelsus) [2] [4] Vomiting Diarrhea Constipation Abdominal pain or discomfort Dyspepsia These effects are typically dose-dependent and most pronounced during the initial titration phase, with higher rates observed at weight management doses compared to diabetes doses

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This conversation should always be interpreted with a qualified healthcare provider