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In contrast, no benefits on the rate of decline in glomerular filtration rate have been seen in trials of DPP-4 inhibitors, perhaps because the renal actions of DPP-4 inhibitors are primarily mediated by potentiation of SDF-1, not GLP-1

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Maintain metabolic health.*

Why GLP-1 Receptor Agonists Are Becoming Essential Cardiovascular Drugs Introduction Glucagon-like peptide-1 receptor agonists (GLP-1RAs)have emerged as a transformative class of medications in the management oftype 2 diabetes, demonstrating an approximate 14 percent reduction in major adverse cardiovascular events

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