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Ozempic has been considered a wonder drug for managing blood sugar in people with type-2 diabetes, and its built up a reputation for helping people lose significant amounts of weight

Semaglutide is also approved for weight management in people battling obesity, especially those with a Body Mass Index (BMI) of 30 or greater, or a BMI of 27 or above when paired with weight-related conditions such as high cholesterol, type 2 diabetes, or hypertension

Despite this signal, the absolute number of events remained low because NAION is rare

Individual experience varies, which is why some people who cannot tolerate one do fine on the other

The EXSCEL (NCT01144338), HARMONY (NCT02465515), REWIND ( NCT01394952), and AMPLITUDE-O (NCT03496298) trials all demonstrated cardioprotection or near misses for exenatide, albiglutide, dulaglutide and efpeglenatide, respectively

Delivery times can vary, which may cause interruptions in medication schedules