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"Patients finally have an obesity treatment available to them that actually works -- but because of ongoing challenges with supply -- they have to literally hunt down their medication, sometimes calling every pharmacy in their city just to come up empty," he wrote

Cost-effectiveness studies and the incorporation of pharmacoeconomic outcomes (e.g., episodes of hospitalization or other acute care) into late-stage clinical trials can help to generate data needed to understand the balance of benefits and harms for a given intervention (Fillit et al., 2010)

[DOI] [PMC free article] [PubMed] [Google Scholar] 66.Raz I, Fonseca V, Kipnes M, Durrwell L, Hoekstra J, Boldrin M, et al

Combining aerobic exercise (walking, cycling, swimming) with resistance training at least twice weekly helps preserve lean muscle mass, which is critical for maintaining metabolic rate

Insurers may be less incentivized to adopt coverage because they could attract a "more expensive" set of patients than competitors who don't participate, he said