does semaglutide stop working for weight loss maintenance after discontinuing GLP-1 : r/Zepbound Woman shares journey of weight

[DOI] [PubMed] [Google Scholar] 14.Almustanyir S., Alhabeeb H., AlHusseini N., Al Thow M

Abstract Glucagon (GCG) like peptide 1 (GLP-1) has emerged as a powerful player in regulating metabolism and a promising therapeutic target for various chronic diseases

And energy expenditure patterns shift through mechanisms that research is still characterizing

3.1 Sustained Appetite Suppression and Reduced Energy Intake The primary driver of weight loss on GLP-1 therapy is reduced energy intake

As Ethan Berke, MD, MPH, Chief Medical Officer at Teladoc Health, put it perfectly: When something new comes in, we dont always know how to use it

The approved protocol begins with 2.5 mg subcutaneously once weekly for four weeks, serving as an initiation dose to improve gastrointestinal tolerability