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Participants were randomly assigned in a 1:1 ratio to receive either semaglutide 50 mg or a placebo once daily for 68 weeks

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As researcher Anton Pottegard explained to Medscape Medical News, 'This makes the results quite valuable, as they provide reassurance that the recent concern does not seem to be supported by data'

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73 A post hoc analysis suggested that a higher proportion of insulin-resistant patients in the phase 2 trial may have contributed to the discrepant results, because Exenatide PD3 showed a non-significant trend toward benefit only in the small insulin-resistant subgroup

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6 Whether this signal extends to patients who have already experienced an overdose, regardless of their original indication for GLP-1 therapy, has not been established

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Hypertension (Dallas, Tex: 1979)

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Its starting dose is typically 1.5 milligrams (mg) and goes up to 25 mg, according to a press release from Novo Nordisk, the manufacturer of the drug

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