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The SUMMIT trial demonstrated that treatment with tirzepatide reduced the risk of a composite of cardiovascular-related deaths or worsening heart failure, compared with placebo, and improved the health of patients with heart failure with preserved ejection fraction and obesity [147]

Avoid processed snacks and sugary drinks that can undermine your progress

Elevated triglycerides are often linked to insulin resistance, a condition common in those with obesity and type 2 diabetes

GLP-1 therapy can also affect gut health

Although a zinc chloride-based formulation of taspoglutide, facilitating subcutaneous precipitation, showed promising results, phase 3 trials were completed, but a submission for approval was discontinued, due to a number of cases of anaphylactic shock (49, 50)

Miller CR, Wactawski-Wende J, Manson JE, et al