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Glucagon-like peptide-1 (GLP-1) is a hormone involved in glucose homeostasis and satiety regulation

Some sub-analyses of large clinical trials suggest that GLP-1RA and sodium-glucose cotransporter 2 inhibitor combination therapy may provide more significant reductions in heart failure hospitalization and renal composite events than each alone

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The use of glucagon-like peptide-1 receptor agonists (GLP-1RAs), used to treat diabetes and obesity, may be associated with a wide range of health effects, both positive - such as a reduced risk of cardiometabolic disorders - and negative - an increased risk of gastrointestinal conditions or hypertension

Oxyntomodulin and peptide tyrosinetyrosine are gut hormones that act as satiety signals and decrease food intake

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