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10.1111/jnc.15521 J

Fahima Azizi, MD and Dr
4 They also induce satiety by activating GLP-1 receptors in brain centers that regulate appetite, such as the hypothalamus, brainstem nucleus tractus solitarius, and amygdala 5 , and slow gastric emptying, which aids in glycemic control and weight loss

v9i1e52987 [DOI] [PMC free article] [PubMed] [Google Scholar] 31.Silva MN, Vieira PN, Coutinho SR, Minderico CS, Matos MG, Sardinha LB, Teixeira PJ
P = 0.20) [127] (the authors note that data regarding pancreatic cancer are too limited to draw any firm conclusions)

Satiety and Nausea: Both activate satiety centers in the hypothalamus, which may contribute to the nausea commonly seen during drug initiation or dose escalation