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Single dosing with cagrilintide led to comparable reductions in food intake and body weight (Figure 2A,B), and at the highest cagrilintide dose of 300 nmol/kg, the mean percent change from baseline in body weight was 14.5% (SE: 0.8) at day 4 post-dose

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Autoimmune patients planning to stop tirzepatide should taper gradually rather than stopping abruptly, and should have their autoimmune specialist monitor disease activity closely during and after the transition