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Description
A clinically significant interaction exists between tirzepatide and oral contraceptives, requiring backup contraception for 4 weeks after initiation and each dose increase, and patients taking levothyroxine or other time-sensitive medications warrant closer monitoring

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This high prevalence of concurrent chronic conditions creates a cascade of negative consequences
Gallbladder Problems: Semaglutide may increase the likelihood of gallstones or other gallbladder issues

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