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Constipation and GI upset are frequent side effects of GLP-1, which is why Gomer doesnt recommend going keto at the same time or very soon after starting on GLP-1

Tirzepatide (15mg, 72w) 20.9% Mean Reduction Retatrutide (12mg, 48w) 24.2% Mean Reduction Dosing Protocols in Laboratory Research Dosing protocols for these peptides are typically based on a "low and slow" escalation model to minimize gastrointestinal saturation