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You shouldn't take it if you're pregnant, breastfeeding, or planning a pregnancy in the next two months, or if you've had a serious allergic reaction to semaglutide

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Analysis of EHR notes for on-treatment functional features showed reduced exercise tolerance was the strongest correlate of greater LBM loss, increasing by 7.2 and 11.1 percentage points in semaglutide- and tirzepatide-treated patients, respectively

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