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In selected cases meeting NICE criteria for obesity pharmacotherapy (e.g., semaglutide 2.4mg/Wegovy with BMI 35 kg/m with comorbidities or 30 kg/m with weight-related comorbidities, prescribed through specialist weight management services) or bariatric surgery, these interventions may be considered, with specialist input to ensure safe implementation alongside lymphoedema management strategies

33 They found that the HR for developing wet AMD was 2.21 in GLP-1 RA users compared with controls

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This is a proposed rule, not yet finalized

Zhu Y, Zhao S, Deng Y, et al

The highest risk appears to be in patients with type 2 diabetes who have established diabetic retinopathy at the time of treatment initiation, particularly when aggressive glycemic targets are pursued rapidly without appropriate ophthalmologic monitoring