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Can methotrexate cause diarrhea in a patient with a history of Non-Arteritic Anterior Ischemic Optic Neuropathy (NAION) and type 2 diabetes, who is taking Mounjaro (tirzepatide)?

Less Common but Important Side Effects In rare cases, clients might experience more severe gastrointestinal symptoms, such as ongoing vomiting or diarrhea, which can lead to dehydration

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Further, there were significant differences in ODI between treatment groups

Low Hematocrit (Anemia / Hypochromia) Causes: Blood loss (acute or chronic) Nutritional deficiencies (iron, folate, vitamin B12) Hemolytic anemia Chronic disease anemia Symptoms: fatigue, pallor, shortness of breath 2