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Fatty liver: Can lead to fatty liver disease, which may progress to liver dysfunction, cirrhosis, or require liver transplant

The weight loss follows primarily from reduced caloric intake

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The 60mg format provides a higher total peptide concentration than lower-strength alternatives, making it relevant for research environments requiring larger-dose investigational protocols

Analysis of EHR notes for on-treatment functional features showed reduced exercise tolerance was the strongest correlate of greater LBM loss, increasing by 7.2 and 11.1 percentage points in semaglutide- and tirzepatide-treated patients, respectively