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TC: Writing original draft, Methodology, Supervision, Investigation, Conceptualization, Funding acquisition

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The most recently marketed Tirzepatide targets not only the GLP-1 receptors, but also the Glucose-dependent Insulinotropic Polypeptide (GIP) receptors, which have similar important functions in blood glucose regulation

[DOI] [PubMed] [Google Scholar] 54.McGarry A, et al

This protein, Exendin-4, naturally has Glycine as the second amino acid, making it resistant to DPP-4 inactivation

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