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[2] Management of acute pancreatitis is primarily supportive and usually requires hospital admission

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But the doses required (typically 5001,500 mg of berberine per day) are far beyond what a small patch can plausibly deliver through the skin, even before you account for the absorption barrier

Results suggest a potential effect of glutamine on oxidative stress and inflammatory markers

J Clin Pharm Ther (2016) 41:1168