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With GLP-1 pills , the medication sits in the stomach longer, which can lead to more upper-GI symptoms like reflux, stomach pain, and nauseaespecially since the pill must be taken on an empty stomach

Wegovy now comes as a daily tablet as well as the weekly injection

However, most providers manage this by starting you on a very low dose of naltrexone and gradually increasing it, ensuring your body has time to adapt to both medications

In certain situations, more tests could be suggested in order to offer the best advice

Using GLP-1 injections with lifestyle changes supports better outcomes

The full mechanism of action is unclear and may involve electrical neuromodulation of a variety of pathways including visceral hypersensitivity (efferent nociceptive signaling) and gastric (electrical) dysrhythmia