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Key Drug Classes Requiring Provider Review Before Starting GLP-1 Treatment Several medication categories warrant careful evaluation before initiating a GLP-1 receptor agonist

An unfortunate adverse effect of more intensive diabetic therapy is that it increases the risk for hypoglycemia

Biliary complications (cholelithiasis, cholecystitis) represent a class effect attributable to reduced gallbladder motility, with incidence approximately 1.5-2.5-fold higher than placebo in long-term trials
11 Linagliptin is a strong CYP3A4 inducer

And overwhelmingly these drugs have only been available for people who have wealth. Kennedy had previously expressed skepticism to GLP-1s in fighting obesity and diseases related to the condition
