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Identification of dipeptidyl peptidase IV inhibitors: virtual screening, synthesis and biological evaluation

These medicines mimic the action of GLP-1, a naturally occurring hormone produced in the intestine that plays a crucial role in glucose regulation

GLP-1s provide guardrails for patients by reducing their desire, lowering their threshold for nausea, forcing them to drink at a slower pace and exacerbating the hangover, thereby creating a negative feedback loop in which the patient can continue to drink but simply doesnt do so excessively, le Roux said

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doi: 10.1073/pnas.220413597

10.1111/bph.12895 [DOI] [PMC free article] [PubMed] [Google Scholar] 107.Zhao D, Liu J, Wang M, Zhang X, Zhou M