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After 24 weeks of treatment, the trial showed a relative reduction in liver fat content (LFC) by 76.4%, a decrease in serum ALT (alanine aminotransferase) by 15.2 IU/L, and a drop in cT1 levels by 149.7 ms
2014, 307, H1120-1133,
In a clinical trial in pediatric patients aged 12 years and older with normal baseline heart rate, more patients treated with this drug compared to placebo had maximum changes in heart rate of 20 bpm or more (54% vs 39%)

This is the rationale behind Zepbound's mandatory four-week titration steps

Coverage for the medication itself may apply depending on diagnosis, insurance type, and state regulations

Glucagon-induced brown adipose tissue (BAT) thermogenesis has been demonstrated in rodents (37, 54)
