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Most common side effects: Nausea Vomiting Diarrhea Constipation Less common side effects Pancreatitis Inflammation of the pancreas, causing abdominal pain Gastroperesis The stopping or slowing of food moving out of the stomach Bowel obstruction A blockage that prevents food from passing through the intestines Gallstones Gallstone attacks and bile duct blockage Ozempic Face A hollowed look on the face, wrinkles on the face, and a change in the appearance of facial features as a result of rapid weight loss Source [7] GLP-1 medication statistics in the UK Statistics on GLP-1 medication usage in the UK are more limited than in the U.S

Biological activity of the endocannabinoid system Once in the body, 9 -THC and CBD exert their effects via the endocannabinoid system (ECS).The identification of the specific binding sites for 9 -THC in the brain [45], complemented by the cloning of the cannabinoid receptor 1 (CB1), that led to the development of the concept of a cannabinoid receptor system given the binding of 9 -THC to CB1 as a partial agonist [46]

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For that reason, dose adjustments are often considered within a broader metabolic context rather than as isolated dosing tactics

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