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Additionally, GIP directly stimulates lipogenesis, while GLP-1 indirectly promotes lipolysis, collectively maintaining healthy adipocytes, reducing ectopic fat distribution, and increasing the production and secretion of adiponectin from adipocytes

The medications are very effective at helping reduce food intake, but they do nothing for the underlying reasons you were reaching for food to begin with

Saxenda for weight management), dulaglutide (Trulicity, approved for diabetes only), and oral semaglutide (Rybelsus, approved for diabetes only)

JAMA 321(1):6979 Sato T, Aizawa Y, Yuasa S, Kishi S, Fuse K, Fujita S, Ikeda Y, Kitazawa H, Takahashi M, Sato M, Okabe M (2018) The effect of dapagliflozin treatment on epicardial adipose tissue volume

[DOI] [PubMed] [Google Scholar] 26.Kim Y., Seol E.-Y

Wan WW, Qin QK, Xie LS, Zhang HQ, Wu F, Stevens RC, et al