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As muscles adapt to reduced glycogen stores, localized spasms may occur, particularly in larger muscle groups

In children 12 years and older, the rate was 4% versus 0% with placebo

Calignano A, Katona I, Desarnaud F, Giuffrida A, La Rana G, Mackie K, Freund TF, Piomelli D

Compounded semaglutide and tirzepatide are available when clinically appropriate, alongside branded options including Ozempic, Wegovy, Zepbound, and Saxenda

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