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These powerful medications have revolutionized how we treat Type 2 diabetes and obesity

In taste buds, GLP-1 is locally produced from proglucagon through the cleavage by prohormone convertase PC1/3, which is co-expressed with GLP-1 in all taste cells positive for this peptide

Tirzepatide is FDA-approved and commercially available

By performing a GWAS in the tirzepatide-treated population alone (Supplementary Table 12), we identified an association between the vomiting side effect and GIPR (rs71338792, P = 4.2 10 9 , odds ratio = 1.84

[DOI] [Google Scholar] 69.Gubra

Your healthcare provider will carefully evaluate your health history, perform necessary tests, and determine whether tirzepatide is safe and appropriate for your weight management needs