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Criteria include: Eating an abnormally large amount of food Experiencing loss of control Eating far more rapidly than normal Eating until uncomfortably full Consuming large amounts of food when not physically hungry Eating alone out of embarrassment for the quantity Self-loathing, depression, or guilt after overeating Doctors don't consider purging food, vomiting, taking laxatives, or overexercising to be diagnostic criteria for binge-eating disorder, and the behaviors above must occur at least once a week

Association of Kv7.1 with KCNE1 produces channels that activate slowly with a depolarizing voltage and have a unique sensitivity to chromanol 293B, a specific KCNQ1 blocker (Lerche et al., 2007)

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Idiopathic gastroparesis is associated with specific transcriptional changes in the gastric muscularis externa

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