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Lys(9) for Glu(9) substitution in glucagon-like peptide-1(7-36)amide confers dipeptidylpeptidase IV resistance with cellular and metabolic actions similar to those of established antagonists glucagon-like peptide-1(936)amide and exendin (939)

The alterations that occur in this signal transduction pathway may have genetic and/or epigenetic origins

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Understanding the distinction between established adverse effects and theoretical or unconfirmed risks helps patients and providers make informed treatment decisions while maintaining appropriate clinical vigilance

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