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exenatide glp 1 agonist Further support for GLP-1R agonists – The Science of Parkinson's GLP-1 Receptor Agonists and Research
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Furthermore, the STEP-TEENS trial demonstrated semaglutides effectiveness in reducing BMI and cardiometabolic risks in obese adolescents, suggesting its potential for use in younger populations (40)

The drug was conceived as a short-term jumpstart, a way to break inertia and establish new eating patterns while the medication provides a window of reduced appetite

J Clin Endocrinol Metab 80: 952-957, 1995

doi: 10.1007/s11892-007-0056-9 [DOI] [PubMed] [Google Scholar] 120

This builds on his work to understand 'how circulating GLP-1 can produce multiple actions, both directly and indirectly, on multiple organs' which he has pursued for many years with colleagues (McLean, Wong, Campbell)