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Dialysis patients typically require: Higher protein consumption Careful phosphorus management Stable calorie intake Controlled fluid intake If appetite drops too much, patients may struggle to maintain proper nutrition

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The raw data generated for the RNA-seq analysis are available from the NCBI SRA database under the accession code PRJNA1194209

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Consistent with the FAP-based approach, stimulation with PF-06882961 for 30 minutes triggered marked intracellular accumulation of GFP-GLP-1R, which was reversible following a 2-hour washout period