what is glp 1 agonist drugs Evolution of GLP‐1 Receptor Agonists for Diabetes Treatment glp-1_analogs [TUSOM | Pharmwiki]

If weight loss is a treatment goal , GLP-1 medications are a more appropriate choice

Wei L, Mo W, Lan S, et al

Jump to: GLP-1s for type 2 diabetes | GLP-1s for weight loss | Side effects and safety | Take home message GLP-1 receptor agonists (GLP-1s) are a class of medications approved for individuals living with type 2 diabetes and obesity to help lower blood glucose levels (blood sugar) and support weight loss

Specifically, GLP-1RAs downregulate activation of VCAM1, the intracellular adhesion molecule-1 (ICAM-1) and plasminogen activator inhibitor type 1 (PAI-1) in endothelial cells [57]

doi: 10.1161/CIRCRESAHA.114.301958

Preliminary results indicate that such drugs might not only be effective for obesity and diabetes but also for a number of other diseases including osteoarthritis, Parkinson's disease and a range of conditions caused by a buildup of fat in the liver, known as nonalcoholic steatohepatitis (NASH) (Brandt, Mller, DiMarchi)