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Michos, MD, MHS, FACC, FAHA, FASE, FASPC, can be reached at [email protected]

The incidence of all-cause blindness was less often coded for individuals with GLP-1 RA prescriptions compared with those without GLP-1 RA prescriptions (2313 [1.2%] vs 3051 [1.6%] events

GLP-1 agonists, Cleveland Clinic (2023) Nutritional modulation of endogenous glucagon-like peptide-1 secretion: A review , Nutrition & Metabolism (2016) Closing Americas fiber intake gap, American Journal of Lifestyle Medicine (2016) Easy ways to boost fiber in your daily diet, Academy of Nutrition and Dietetics (2021) The impact of short-chain fatty acids on GLP-1 and PYY secretion from the isolated perfused rat colon, The American Journal of Physiology-Gastrointestinal and Liver Physiology (2018) Mediterranean diet effects on Type 2 diabetes prevention, disease progression, and related mechanisms

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However, the timeline for recovery varies considerably between individuals

In animal studies, GLP-1 and its analogs reduced macrophage infiltration in blood vessels, and production of pro-inflammatory cytokines such as IL-6, IL-1, TNF-, and CRP