glp-1 receptor agonists weight loss Medications: Everything You Need to Know Weight Reduction with GLP-1 Agonists

Should discounts be provided for the elimination of comorbidities or for multiple medications associated with diabetes and obesity

Individuals should be screened for signs of eating disorders (binge eating, anorexia nervosa, bulimia nervosa, night eating)

Ndumele, C.E

Given the multiple pathophysiologic targets that exist in the setting of T2DM, it is common to encounter patients who require the use of multiple antihyperglycemic agents to successfully reach treatment goals

Sex Differences in Response to Treatment with Glucagon-like Peptide 1 Receptor Agonists: Opportunities for a Tailored Approach to Diabetes and Obesity Care

SGLT-2 inhibitors act primarily in the renal proximal tubule and have no established direct actions on mesolimbic reward circuits in the brain.63 On the contrary, neurotropism is a distinct property of GLP-1 receptor agonists.62 GLP-1 is produced in the brain, GLP-1 receptors are present in areas of the brain involved in impulse control and reward signalling, and a pharmacologically administered exogenous GLP-1 receptor agonist crosses the blood-brain barrier and enters the brain within minutes, strengthening the inference that the observed GLP-1 receptor agonist anti-addictive properties are likely specific and biologically plausible drug effect of GLP-1 receptor agonism, distinct from the general benefits of treating diabetes that would be expected with both SGLT-2 inhibitors and GLP-1 receptor agonists.6465 These observational findings do not by themselves justify the prescribing of GLP-1 receptor agonists specifically to prevent or treat SUDs