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Involvement of glucagon-like peptide-1 in the regulation of selective excretion of sodium or chloride ions by the kidneys

Reported and produced by Sophie Braybrook, Samantha Everett, Helen Johnson, Ian Watkins and Girish Juneja

Sin embargo, su eficacia no se limita al descenso de peso

GLP-1 receptor agonists work by: Stimulating insulin secretion from pancreatic beta cells in a glucose-dependent manner Suppressing glucagon release when blood glucose levels are elevated Slowing gastric emptying, which moderates post-meal glucose rises (this effect may attenuate over time) Reducing appetite through effects on brain centres controlling satiety Understanding this pharmacological profile is essential when considering the hypoglycaemic potential of Wegovy

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