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doi: 10.2174/1570159X18666200528142429 31 AlberdiEWyssenbachAAlberdiMSnchez-GmezMVCavaliereFRodrguezJJet al

Evidence from Animal Models: Preclinical Studies Novel incretin analogs including exendin-4 were found to improve autophagy and protect from mitochondrial stress induced by a toxic mitochondrial complex I inhibitor, rotenone in dopaminergic SH-SY5Y neuroblastoma cells, increasing the survival of SH-SY5Y cells [36]

In the central nervous system, the action of GLP-1 and GLP-1RAs on its receptors can affect a variety of brain functions including satiety, thermogenesis, influence blood pressure, neurogenesis, neurodegeneration, retinal repair, and change energy homeostasis [16-20]

Metabolic hormones, apolipoproteins, adipokines, and cytokines in the alveolar lining fluid of healthy adults: Compartmentalization and physiological correlates