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Many asked if you will gain the weight back if you stop the medication

When activated by medications like retatrutide, it slows gastric emptying, increases insulin secretion, reduces appetite, and (unexpectedly) affects liver enzyme expression including Cyp2e1

When the elimination half-life is much shorter than the dosing interval, accumulation is negligible, and steady-state exposure approximates single-dose exposure ( The accumulation factor (R) for repeated dosing at a fixed interval can be derived from standard pharmacokinetic theory and approximated as: Where k is the elimination rate constant (k = 0.693/t) and is the dosing interval
