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Meanwhile, Altimmune has repurposed its dual GLP-1/glucagon agonist, pemvidutide, in a Phase II trial focused on reducing heavy drinking days as a primary endpoint

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With a median follow-up duration of 26 weeks, a total of 177 randomized controlled trials involving 165,081 participants were included

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GLP-1RAs provide different mechanistic effects including anti-oxidative, anti-inflammatory, and anti-atherosclerotic properties [4, 9, 11, 14, 17]